Variant acute promyelocytic leukemia translocation (15;17) originating from two subsequent balanced translocations involving the same chromosomes 15 and 17 while preserving the PML/RARA fusion

Abstract

Fluorescence in situ hybridization (FISH) analysis of the bone marrow of a 24-year-old man diagnosed with acute promyelocytic leukemia (APL) revealed a variant pattern with one fusion signal instead of the typical two fusions expected with the probe set used. The combined FISH and conventional chromosome analyses suggested that two subsequent translocations had occurred in this patient involving the same chromosomes 15 and 17. As the prognostic outcome in APL is strictly associated with the presence of a PML/RARA fusion, it is useful and necessary to perform both cytogenetic and FISH analyses of a variant t(15;17) to determine the status of the PML/RARA fusion.  2005 Elsevier Inc. All rights reserved.
Download the full paper HERE.

34 comments

  • JohnnyDup
    JohnnyDup 23 Aug 2017

    buy levitra online usa
    levitra
    cialis viagra levitra for sale
    levitra cost
    buy levitra australia

    reply
  • JohnnyDup
    JohnnyDup 23 Aug 2017

    levitra sale walmart
    levitra online
    cheapest levitra online
    levitra online
    levitra for cheap

    reply
  • JohnnyDup
    JohnnyDup 23 Aug 2017

    order levitra no prescription
    buy levitra
    buy levitra online ireland
    levitra online
    buy levitra and cialis

    reply
  • CharlesHenue
    CharlesHenue 22 Aug 2017

    when will generic viagra be sold
    Buy Generic Viagra
    generico do viagra em curitiba
    Buy Viagra Online
    yohimbe viagra together

    reply
  • GeorgePoela
    GeorgePoela 19 Aug 2017

    order levitra from canada
    buy levitra
    levitra at a discount
    levitra cost
    cheap genuine levitra

    reply
  • RobertAlect
    RobertAlect 18 Aug 2017

    can you buy levitra over the counter
    buy levitra online
    cheap levitra in canada
    buy levitra online
    buy cialis levitra

    reply
  • PeterBup
    PeterBup 18 Aug 2017

    buy viagra online in dubai
    cheap generic viagra
    viagra buy online usa
    viagra generic
    viagra 100 mg filmtabletta

    reply
  • JosephGuaxy
    JosephGuaxy 15 Aug 2017

    real money slots ios
    slots online
    ontario online gambling sites
    slots online
    online casino real money ipad

    reply
  • Robertanise
    Robertanise 15 Aug 2017

    online roulette king
    roulette
    play blackjack online yahoo
    roulette online
    online casino legal in singapore

    reply
  • HaroldexilK
    HaroldexilK 12 Aug 2017

    video poker games
    u s casino online
    online gambling in north carolina
    online casino usa news
    live blackjack casino online

    reply